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{"id":2039,"date":"2017-02-08T12:02:20","date_gmt":"2017-02-08T12:02:20","guid":{"rendered":"https:\/\/offhealth.netseven.work\/approfondimento\/glaucoma\/"},"modified":"2024-05-09T14:02:07","modified_gmt":"2024-05-09T14:02:07","slug":"glaucoma","status":"publish","type":"approfondimento","link":"https:\/\/offhealth.netseven.work\/en\/approfondimento\/glaucoma\/","title":{"rendered":"Glaucoma"},"content":{"rendered":"\n<h4 class=\"wp-block-heading\">What is it?<\/h4>\n\n<p>Glaucoma is a progressive neurodegenerative disease that preferentially occurs at the optic nerve papilla, but evolves to affect all structures of the optic pathways.&#13;\n<\/p>\n\n<p><span style=\"font-weight: 400;\">Axons and glial structures of the papilla and retrobulbar optic tract are affected in the process; on examination of the ocular fundus, the papilla may show more or less marked excavation.&#13;\n<\/span><span style=\"font-weight: 400;\">Early functional disorders are diagnosable only by perimetry (paracentral arciform scotomas); at a more advanced stage there is decreased visual acuity.<\/span>&#13;\n&#13;\n<span style=\"font-weight: 400;\">\u00a0<\/span><\/p>\n\n<p>These dysfunctions, together with morphologically recognizable changes, constitute &#8221; glaucoma damage.&#8221;&#13;\n<\/p>\n\n<p>The result of this is damage that corresponds to the loss of some of the nerve fibres as they exit the eyeball through the optic papilla to form the optic nerve.&#13;\n<\/p>\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" data-src=\"https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/1_glaucoma2-300x180-1.jpg\" alt=\"\" class=\"wp-image-1201 lazyload\"\/><noscript><img decoding=\"async\" width=\"300\" height=\"180\" src=\"https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/1_glaucoma2-300x180-1.jpg\" alt=\"\" class=\"wp-image-1201 lazyload\" srcset=\"https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/1_glaucoma2-300x180-1.jpg 300w, https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/1_glaucoma2-300x180-1-125x75.jpg 125w, https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/1_glaucoma2-300x180-1-150x90.jpg 150w, https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/1_glaucoma2-300x180-1-230x138.jpg 230w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/noscript><figcaption class=\"wp-element-caption\"><em><span style=\"font-size: 8pt; line-height: 115%; font-family: Verdana, sans-serif; color: #a6a6a6; background-image: initial; background-attachment: initial; background-position: initial;\">Photo concession: Dott. C. <em style=\"text-align: justify;\"><span style=\"font-size: 8pt; line-height: 12.2666673660278px; font-family: Verdana, sans-serif; color: #a6a6a6; background-image: initial; background-attachment: initial; background-position: initial;\"><em><span style=\"font-size: 8pt; line-height: 12.2666673660278px; background-image: initial; background-attachment: initial; background-position: initial;\">Benedetti<\/span><\/em><\/span><\/em><\/span><\/em><\/figcaption><\/figure>\n\n<h4 class=\"wp-block-heading\">Types of Glaucoma<\/h4>\n\n<ul class=\"wp-block-list\">\n<li>open angle glaucoma<\/li>\n\n\n\n<li>angle-closure glaucoma<\/li>\n\n\n\n<li>normal pressure glaucoma<\/li>\n\n\n\n<li>congenital glaucoma (present at birth)<\/li>\n\n\n\n<li>secondary glaucoma<\/li>\n<\/ul>\n\n<p>All these forms, although different, have as a common end result progressive and irreversible damage to the optic nerve.&#13;\n<\/p>\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" data-src=\"https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/1_papille-300x236-1.jpg\" alt=\"\" class=\"wp-image-1203 lazyload\"\/><noscript><img decoding=\"async\" width=\"300\" height=\"236\" src=\"https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/1_papille-300x236-1.jpg\" alt=\"\" class=\"wp-image-1203 lazyload\" srcset=\"https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/1_papille-300x236-1.jpg 300w, https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/1_papille-300x236-1-95x75.jpg 95w, https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/1_papille-300x236-1-242x190.jpg 242w, https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/1_papille-300x236-1-248x195.jpg 248w, https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/1_papille-300x236-1-150x118.jpg 150w, https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/1_papille-300x236-1-230x181.jpg 230w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/noscript><figcaption class=\"wp-element-caption\"><em><span style=\"font-size: 8pt; line-height: 115%; font-family: Verdana, sans-serif; color: #a6a6a6; background-image: initial; background-attachment: initial; background-position: initial;\">Photo concession: Dott. C. <em style=\"text-align: justify;\"><span style=\"font-size: 8pt; line-height: 12.2666673660278px; font-family: Verdana, sans-serif; color: #a6a6a6; background-image: initial; background-attachment: initial; background-position: initial;\"><em><span style=\"font-size: 8pt; line-height: 12.2666673660278px; background-image: initial; background-attachment: initial; background-position: initial;\">Benedetti<\/span><\/em><\/span><\/em><\/span><\/em><\/figcaption><\/figure>\n\n<p><\/p>\n\n<p>The effect of glaucoma is a progressive reduction of the visual field, starting from the most peripheral areas and affecting, in the most advanced stage, the central part of the visual field itself.&#13;\n<\/p>\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" data-src=\"https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/progressioneCV-300x150-1.jpg\" alt=\"\" class=\"wp-image-1205 lazyload\"\/><noscript><img decoding=\"async\" width=\"300\" height=\"150\" src=\"https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/progressioneCV-300x150-1.jpg\" alt=\"\" class=\"wp-image-1205 lazyload\" srcset=\"https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/progressioneCV-300x150-1.jpg 300w, https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/progressioneCV-300x150-1-130x65.jpg 130w, https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/progressioneCV-300x150-1-150x75.jpg 150w, https:\/\/offhealth.netseven.work\/app\/uploads\/2024\/04\/progressioneCV-300x150-1-230x115.jpg 230w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/noscript><figcaption class=\"wp-element-caption\"><em><span style=\"font-size: 8pt; line-height: 115%; font-family: Verdana, sans-serif; color: #a6a6a6; background-image: initial; background-attachment: initial; background-position: initial;\">Photo concession: Dott. C. <em style=\"text-align: justify;\"><span style=\"font-size: 8pt; line-height: 12.2666673660278px; font-family: Verdana, sans-serif; color: #a6a6a6; background-image: initial; background-attachment: initial; background-position: initial;\"><em><span style=\"font-size: 8pt; line-height: 12.2666673660278px; background-image: initial; background-attachment: initial; background-position: initial;\">Benedetti<\/span><\/em><\/span><\/em><\/span><\/em><\/figcaption><\/figure>\n\n<p><\/p>\n\n<p>Scotomas (blind areas) are only perceived by the patient at a late stage when the optic nerve damage is already advanced. For this reason, glaucoma is also called the &#8216;silent thief of sight&#8217;. This is why it is essential that all patients over the age of 40 have their eye pressure checked at least every two years. Glaucoma is also affected by hereditary aspects, which is why it is advisable to have an earlier and more frequent check-up in family members of people with glaucoma.&#13;\n<\/p>\n\n<p>Ocular pressure is determined by the liquid that fills the eye: aqueous humour. The aqueous humour also enables the eye to maintain its more or less spherical shape. This is continuously being produced but at the same time must also be eliminated. An imbalance in this dynamic can lead to increased intra-ocular fluids and at the same time increased pressure.&#13;\n<\/p>\n\n<p>There are various instruments called tonometers for measuring tone. The most common ones require the use of an anaesthetic eye drops as they have to be in contact with the eye even if only for a few moments.&#13;\n<\/p>\n\n<p>There is also the so-called &#8216;blowing&#8217; tonometer, which does not require the use of drugs.&#13;\n<\/p>\n\n<p>In both the former and the latter case, it is a quick and absolutely painless and non-traumatic examination, which one can undergo with extreme peace of mind.&#13;\n<\/p>\n\n<p><span style=\"font-weight: 400;\">In the case of open-angle glaucoma, it is the ineffectiveness of the aqueous humour outflow system, known as the trabecularis, that leads to increased pressure. In rarer cases, there may be overproduction.<\/span><\/p>\n\n<p><span style=\"font-weight: 400;\">In the case of angle-closure glaucoma, it is the internal structure of the eye that causes an anatomical alteration of the outflow system, which narrows, thus reducing the passage of aqueous humour to be eliminated.<\/span><\/p>\n\n<p><span style=\"font-weight: 400;\">In the case of normal pressure glaucoma, one consideration must be made: not all of us are equally sensitive to pressure variations. Most likely, glaucoma patients with normal pressure are so sensitive to intraocular pressure that they show the typical signs of glaucoma even if the tone is measured normally. Conversely, there are people who, despite manifesting an above-normal tone for years, never develop glaucoma.<\/span><\/p>\n\n<p>Damage to the optic nerve caused by glaucoma is irreversible. What one can do is to plan with one&#8217;s ophthalmologist scheduled measurements of eye tone and to keep pressure under control with numerous eye drops capable of lowering eye pressure within the normal range. If, as is sometimes the case, medication is insufficient, laser or surgical treatments can be used to improve the outflow of the aqueous humour.&#13;\n<\/p>\n\n<p>As glaucoma is a neurodegenerative disease, it shares some characteristics with other neurodegenerative diseases such as Alzheimer&#8217;s disease, Parkinson&#8217;s disease, and others.&#13;\n<\/p>\n\n<p><strong>The common characteristics of these diseases are:<\/strong><\/p>\n\n<ul class=\"wp-block-list\">\n<li>death by apoptosis of specific neuronal populations (retinal ganglion cells in glaucoma)&#13;\n<\/li>\n\n\n\n<li>transynaptic degeneration (which leads to alterations in glaucoma along the entire optic pathway)&#13;\n<\/li>\n\n\n\n<li>the progression of the disease over time<\/li>\n<\/ul>\n\n<p><span style=\"font-weight: 400;\"><strong>NEUROPROTECTION<\/strong> represents one more opportunity to intervene on GLAUCOMA.<\/span><\/p>\n\n<p>The purposes of neuroprotection are:<\/p>\n\n<p><span style=\"font-weight: 400;\">1) prevent retinal ganglion cell death<\/span><span style=\"font-weight: 400;\">&#13;\n<\/span><span style=\"font-weight: 400;\">2) repair or regenerate degenerating neuronal cells<\/span><span style=\"font-weight: 400;\">&#13;\n<\/span><span style=\"font-weight: 400;\">3) slow down disease progression.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>What is it? Glaucoma is a progressive neurodegenerative disease that preferentially occurs at the optic nerve papilla, but evolves to&#8230;<\/p>\n","protected":false},"featured_media":0,"parent":0,"template":"","categoria":[43],"class_list":["post-2039","approfondimento","type-approfondimento","status-publish","hentry","categoria-patologia-comune-en"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Glaucoma: causes, symptoms, and treatment | OffHealth<\/title>\n<meta name=\"description\" content=\"Glaucoma is a progressive neurodegenerative disease that preferentially occurs at the level of the optic nerve papilla.\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Glaucoma: causes, 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